Primary Kinetic Isotope Effect for Phenylation with Phenyl Radical
نویسندگان
چکیده
منابع مشابه
A significant improvement of the efficacy of radical oxidant probes by the kinetic isotope effect.
The accurate and sensitive detection of radical oxidants is a central problem in the field of chemical biology. Radical oxidants can be detected in vitro with fluorescent leucodyes such as dihydroethidium (DHE), dihydrorhodamine (DHR), the hydrocyanines, redoxfluor-1, and their organelle-specific analogues. Although these probes are widely used in cell culture, their accuracy is compromised by ...
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Kinetic isotope effects (KIEs) [9] are the effects on chemical reaction rates caused by isotopic substitution in the reacting system. KIEs report on bonding changes to the isotopic atom(s) when going from reactant state to transition state (TS). KIE studies are therefore of great use in solving mechanistic problems such as: (i) concerted or stepwise reaction? (ii) which is the rate limiting ste...
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Methane is the second most important long-lived greenhouse gas and plays a central role in the chemistry of the Earth’s atmosphere. Nonetheless there are significant uncertainties in its source budget. Analysis of the isotopic composition of atmospheric methane, including the doubly substituted species CH3D, offers new insight into the methane budget as the sources and sinks have distinct isoto...
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We have found that photo-excited indigo carmine causes stepwise proton transfer to generate monoalcohol intermediate, which immediately returns to the parent molecule [I. Iwakura, A. Yabushita, T. Kobayashi, Chem. Lett. 38 (2009) 1020]. The kinetic isotope effect in the proton transfer of this system has been studied by direct observation of the real-time molecular vibrational amplitude during ...
متن کاملTriflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides.
The reaction of N-acylaminoalkyl diethylacetals with triflic acid in benzene gave N-acylamino-diphenylalkyls. The proposed intermediates are the N-acyl-2-phenyl cyclic amides, which themselves are similarly converted to N-acylamino-diphenylalkyls.
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1969
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.42.2738